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The blood

As APS is an autoimmune condition of the blood it is not surprising that the blood itself can be affected in several ways:

Low platelet count

A low or reduced platelet count, known medically as thrombocytopenia, is the most common blood related disorder found in APS patients.


Anaemia is associated with a number of chronic conditions, including APS, and is caused by a low level of haemoglobin in the blood.

Thrombotic thrombocytopenic purpura (TTP)

TTP is a rare and very serious blood condition in which very small clots form within the circulating blood; these clots then consume the platelets and cause the platelet count to drop. Antiphospholipid antibodies (aPL) have been found in a number of patients, but the exact association between TTP and APS is still unknown.


Leukopenia is a blood disorder where there is a decrease of the white blood cells in the circulating blood. It is commonly seen in other autoimmune conditions such as lupus and Sjogrens syndrome, but only rarely in APS patients.

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