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The skin

The two most common skin conditions associated with APS are:

Livedo reticularis

About a fifth of APS patients have a skin condition called livedo reticularis, that seems to affect women more than men.

Skin ulcers

Poor circulation, especially in the lower part of the legs, can sometimes cause skin ulcers.

Skin necrosis

In addition to these two well-recognised symptoms, in a very small minority of patients, skin necrosis can occur.


The nails can also be affected in a small number of patients with APS. Small lines of blood, known medically as splinter haemorrhages, appear as little red or brown streaks underneath the nail. They result from clots that damage the tiny blood vessels and tend to appear in several nails.

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